TGFB1 and Familial prostate cancer: Prostate cancer metastasis formation is, among other proteins, influenced by EphA2 [77], steroid receptor coactivator (SRC) family tyrosine kinases [78], FAK [79,80], PKM2 [81], TGFβ [82], TNFα [83], and chemokine signaling at every step of the metastatic process.