Of clinical findings: obesity, WBC, AST, D-dimer PT, CRP, lactate, LDH, and total bilirubin as well as lower PaO2/FiO2, lymphocyte count and albumin to be significantly associated with ICU outcome (Table 4), which is again consistent with previous reports on associations of obesity, liver dysfunction, lymphocytopenia, coagulopathy, malnutrition, renal dysfunction, and cardiac injury with COVID-19 severity or mortality. The gene discussed is CRP; the disease is Abnormal renal physiology.