BACE1 and early-onset autosomal dominant Alzheimer disease: The nature of the linker and its length rely on empiric trials, as was reported for SiR‐probes that target tubulin[59] as well as the protease BACE1 (β‐site amyloid precursor protein‐cleaving enzyme 1) that is involved in Alzheimer's disease.[162] Predictive approaches, guided by in silico calculations similar to other themes,[163] to accelerate such designs would be beneficial for the community.