Considering that the JNK/c‐Jun pathway is over‐activated in more than 80% oesophageal adenocarcinoma specimens,25 and YAP‐TEAD can monitor the progression of basal cell carcinoma via JNK/c‐Jun pathway,18 we set out to investigate the same pathway in EC. The gene discussed is YAP1; the disease is esophageal adenocarcinoma.