However, in a cohort of 177 patients with biopsy-proven GCA [10], eighteen (10.2%) showed normal values of both ESR and CRP (defined as an ESR value of ≤ 22 mm/h in men and ≤ 29 mm/h in women, and a value of CRP ≤ 8 mg/L), at the time of diagnosis. The gene discussed is CRP; the disease is temporal arteritis.