IL1B and liver dysplastic nodule: Additionally, using db/db mice, miR-544 is found to significantly attenuate inflammatory cell infiltration and IL-1 production to suppress glomerulosclerosis and inflammation and eventually ameliorate diabetic renal injury by directly targeting fatty acid synthase, suggesting that miR-544 has anti-inflammatory therapeutic potential for DN treatment (Sun T. et al., 2019) (Figure 5).