Several cell lines have been engineered to be able to study NB in vitro, particularly, IMR-32, a MYCN amplified neuroblastic (N-type) adherent cell-line, obtained in 1967 from a biopsy of an abdominal mass of a 13-month-old Caucasian boy diagnosed with NB with rare areas of organoid differentiation (20). Here, MYCN is linked to neuroblastoma.