SH2B3 and cranioectodermal dysplasia: Several studies have been performed to integrate expression quantitative trait loci (eQTLs) with CeD GWAS associations (Dubois et al., 2010; Kumar et al., 2015; Ricaño-Ponce et al., 2016), and several candidate genes, including UBASH3A, CD274, SH2B3, and STAT4 (Zhernakova et al., 2011), have been identified, implicating T cell receptor, nuclear factor (NF)κB, and interferon (IFN) signaling pathways as biological pathways associated with CeD pathology.