We found that pNK cells from healthy controls, following 72 hs of exposure to the CM of three different PCa cell lines (PC-3, DU-145, LNCaP) showed increase expression of the CD9, CD49a of CXCR4 (*p ≤ 0.05, **p ≤ 0.01) (Figures 6A, B). This evidence concerns the gene ITGA1 and posterior cortical atrophy.