We found that circulating PCa pTA-NKs were able to express larger amount of the pro-inflammatory and pro-angiogenic factors VEGF, CXCL8, CXCL12, PAI, as compared to those from controls, introducing a new scenario for the possible pro-inflammatory and pro-angiogenic activities of circulating NK cell in PCa. The gene discussed is VEGFA; the disease is posterior cortical atrophy.