Real-time PCR results showed that HUVE cells, exposed for 24 h to CM from PCa-ADK pTA-NKs have a pro-inflammatory phenotype with increased mRNA expression of VEGF (*p ≤ 0.05), VEGF-R2, CXCL8 and of factors involved in vascular inflammation and immune cells mobilization, such as CXCR4 (*p ≤ 0.05), CXCL12 (**p ≤ 0.01), ICAM-1 (**p ≤ 0.01), VCAM-1, together with induction of IL-1α (***p ≤ 0.001) (Figure 3C). Here, KDR is linked to posterior cortical atrophy.