We also observed that THP-1 differentiated macrophages, following 72 h of exposure to PCa pTA-NK CMs, displayed increased expression of the M2-like/TAM factors, such as CD206/Mannose receptor, Arg1 (*p ≤ 0.05), IL-10 (**p ≤ 0.01), TGFβ, CXCL8 (***p ≤ 0.001) and decreased expression of the M1-like cytokine IL-12 (*p ≤ 0.05) (Figure 4C). Here, ARG1 is linked to posterior cortical atrophy.