MMP9 and posterior cortical atrophy: We found that CM of pNK cells isolated PCa-ADK samples have higher contents of the pro-inflammatory and tissue-remodelling factors CXCL8/IL-8 (****p≤0.0001), MMP-1 (*p≤0.05), MMP-9 (****p≤0.0001), uPAR (****p≤0.0001) (Figure 3A, Supplementary Figure 2).