Finally, we confirmed by RT-qPCR that the levels of miR-196a-5p were increased more than nine-fold in LSC-enriched CD34+CD38−CD26+ (BCR-ABL1+) vs. CD26-(BCR-ABL1−) fractions from CML-CP patients at diagnosis, and in silico analysis revealed a significant association to lipid metabolism and hematopoiesis functions. The gene discussed is DPP4; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.