SOD1 and major depressive disorder: In STZ-induced diabetic rats, garlic (Allium sativum L.)(0.5 g/kg, gavage, 10 days) treatment also decreased the total duration of immobility, attenuated MDA levels, and increased SOD and glutathione peroxidase (GSH-Px) activities, indicating that garlic alleviates depression-related behaviors partly by attenuating brain oxidative stress (Rahmani et al., 2020).