AIF1 and Stroke: Already during the phase of early acute inflammation at 24 h post-stroke, ADA-409-052 suppressed the stroke-induced expression of Gfap in the ipsilateral peri-ischemic area (from 1.059 ± 0.397 to 0.793 ± 0.197; p < 0.05; Fig. 6a), while the expression of Aif1 remained unchanged at the given time point (Fig. 6b).