AIF1 and ischemia: Since ADA-409-052 provided a mild protection against inflammation-induced neuronal death in vitro, we evaluated whether ADA-409-052 ameliorates ischemia-induced inflammation by analyzing the expression of astrocytic Gfap, and allograft inflammatory Aif1 encoding ionized calcium-binding adapter molecule 1 (Iba1), a commonly used microglia marker.