Genes significant for the CBTTC dataset but not for TCGA glioma dataset included important oncogenes such as MYB, FOXR1, TERT, MET, MYC, and MYCN. For the 13 CBTTC pediatric brain tumor types with the most tumors (13 or more tumors), we evaluated significant SSV-gene associations separately by tumor type. This evidence concerns the gene MYC and central nervous system cancer.