To investigate the clinical relevance of this newly discovered AKT regulation of PDGFRα in human cancer tissues, we analyzed The Cancer Genome Atlas (TCGA) RNA-seq datasets for a correlation between PDGFRα expression and PI3K-AKT signaling pathway activity in the tumors of breast cancer patients with Gene Set Enrichment Analysis (GSEA). This evidence concerns the gene PDGFRA and breast carcinoma.