Subtype-specific AS events in different CERS genes such as CERS2 in Luminal B subtype and CERS4 in Basal subtype suggest a strong subtype-specific post-transcriptional regulation of CERS genes that may play a role in breast cancer pathogenesis (Fig. 2F, G; Data set 8, 9). This evidence concerns the gene CERS4 and breast cancer.