IPA was used for classical pathway analysis and revealed that DEGs were significantly enriched in HER2 breast cancer, non-small cell lung cancer, and melanoma signaling pathways (Supplementary Fig. S9a), while IPA disease and biological function analysis detected significant enrichment of cancer and organismal injuries and abnormalities (Supplementary Fig. S9b). This evidence concerns the gene ERBB2 and non-small cell lung carcinoma.