GSTM3 and cancer: However, molecular research in cervical cancer cells has revealed that GSTM3 upregulation is associated with promoting cancer cell survival, proliferation, tumor progression, and aberrant nuclear factor kappa B (NF-κB) and mitogen-activated protein kinase signaling44; therefore, further research is required to clarify whether GSTM3 plays a role in EGFR-mutant LUAD.