H&E staining and IHC with anti-KIT antibody using formalin-fixed paraffin-embedded (FFPE) liver sections from each group also supported that TGF-β1-mediated GF to CAF transdifferentiation increased GIST liver metastases (Fig. 6e; Supplementary Fig. S4c). The gene discussed is KIT; the disease is gastrointestinal stromal tumor.