Some of these monoallelic deletions include FAS (the cell death receptor), GOT1, and GLUD1 (involved in glutamine metabolism), PGAM1 (a glycolysis gene), HIF1AN (HIF1α inhibitor), and MGMT (a gene known to provide TMZ resistance in GBM through promoter methylation). The gene discussed is GOT1; the disease is glioblastoma.