ABCB7 and macrophage activation syndrome: An expert consensus panel published validated diagnostic criteria for MAS complicating soJIA in 2016 [32]: persistent fever in a patient with soJIA with serum ferritin level > 684 ng/ml plus any of the following: platelet count < 181*10^9/l, ASAT > 48 units/l, triglyceride concentration > 156 mg/dl or fibrinogen < 360 mg/dl [12].