CD40LG and rheumatoid arthritis: Further, levels of IgM antibodies against anti-THRB328−345 in RA patients was greatly higher than HCs by 1.20-fold (p = 0.0149, Fig. 3o, left panel), and AUC values were 0.63 (with 63.3% sensitivity and 53.3% specificity) and 0.56 (with 60.0% sensitivity and 53.3% specificity) for detecting RA and OA (Table 2).