However, IgG anti-CFAH1121−1230, IgG anti-CFAH1121−1230 HNE, IgM anti-CFAH1121−1230, and IgM anti-CFAH1121−1230 HNE were not significantly correlated with DAS28-CRP, RF, CRP, ESR, or HNE-protein adducts, respectively (Table 3); but, IgG anti-CFAH1121−1230 (OR 3.293), IgG anti-CFAH1121−1230 HNE (OR 2.808), IgM anti-CFAH1121−1230 (OR 5.204), and IgM anti-CFAH1121−1230 HNE (OR 2.700) showed risks for RA development (Table 4). The gene discussed is CRP; the disease is rheumatoid arthritis.