These results can be interpreted to mean that neuroinflammatory brain disorders and chronic neurodegeneration such as Alzheimer’s disease could be due to a relative deficiency of these anti-inflammatory molecules (LXA4, resolvins, protectins and maresins and their precursors such as AA, EPA and DHA) and an excess of pro-inflammatory cytokines IL-6, TNF-α and PGs, LTs and TXs. This evidence concerns the gene CD59 and Alzheimer disease.