NOS2 and non-small cell lung carcinoma: CD14-positive/S100A9-positive inflammatory monocytes, which are a distinct subset of myeloid-derived suppressor cells suppressing T cells by arginase, inducible nitric oxide synthase (iNOS), and the IL-13/IL-4Rα axis in patients with NSCLC, have been associated with poor response to chemotherapy [158].