RNF213 and multiminicore myopathy: One study found that RNF213-associated miRNA levels were dysregulated in the serum of MMD patients, such as upregulated miR-106b, miR-130a, and miR-126, and downregulated miR-125a-3p, which is related to the ordinary regulation of VEGF and matrix metalloproteinase 11 (MMP11) [49].