In accordance with these data, we noticed that in COPD patients the C allele of TRPM8 rs11562975 had a trend to association with lower post-bronchodilator FEV1/FVC (GG—48.9 (41.4–55.8)%, GC—45.7 (38.1–50.9)%, CC—35.2 (32.7–37.7)%). This evidence concerns the gene TRPM8 and chronic obstructive pulmonary disease.