VRK1 and cardiomyopathy: The patient was a heterozygous carrier of VUS in DNA methyltransferase 1 (DNMT1) gene (c.1043C> T), and VRK serine/threonine kinase 1 (VRK1) gene (c.8G>A), in addition to dynamin 2 (DNM2) gene (c.2576_2578delCCA), which is associated with severe cardiomyopathies [37].