In a German cohort, the presence of the deleted form has been associated with SS [9] and NHL susceptibility [10], while in a Chinese population, the presence of the functional LILRA3 variant increased disease susceptibility for both SS and active systemic lupus erythematosus (SLE), along with the presence of serum anti-Ro/SSA and anti-La/SSB antibodies and leucopenia [20,21], both previously shown to serve as high risk predictors for SS related lymphoma [22,23]. This evidence concerns the gene TRIM21 and lymphoma.