Therefore, the methodology we describe might help standardize HD diagnosis among genetic laboratories, with implications for genetic pathologies other than HD, e.g., Fragile X (FMR1 gene) [38], ALS/FTD (C9orf72 gene) [39], and Myotonic Dystrophy Type I (DMPK gene) [40], while providing the sensitivity and versatility to detect a broader spectrum of allelic conditions within HD itself. The gene discussed is C9orf72; the disease is frontotemporal dementia.