Gonzalo-Calvo D, Cenarro A, Martinez-Bujidos M, Badimon L, Bayes-Genis A, Ordonez-Llanos J, et al. Circulating soluble low-density lipoprotein receptor- related protein 1 (sLRP1) concentration is associated with hipercolesterolemia: a new potential biomarker for atherosclerosis. The gene discussed is LRP1; the disease is atherosclerosis.