LYZ and infection: PGLYRP-1 functions synergistically in vitro with other antimicrobials (e.g. lysozyme), so potential benefit as an antimicrobial cannot be ruled out considering that pglyrp-1−/− mice are more susceptible to infections (Liu et al., 2000; Wang et al., 2007; Dziarski et al., 2003; Ghosh et al., 2009; Gupta et al., 2020; Osanai et al., 2011).