IGHE and asthma: Interestingly, some individuals are predisposed at birth to generating T2 responses ex vivo to common asthma triggers (e.g. aeroallergens) or having detectable IgE concentrations in cord blood but neither has been shown to predict asthma later in life (Schaub et al., 2005; Turturice et al., 2017a; Shah et al., 2011).