For example, Cheng et al found that the increased UCA1 expression in EGFR‐TKI‐resistant NSCLC cells results in hyperactivation of AKT/mTOR signaling pathway, whereas downregulation of UCA1 in these cells partially restore sensitivity to EGFR‐TKI.30 This evidence concerns the gene AKT1 and non-small cell lung carcinoma.