RB1 and adrenal cortex carcinoma: Mutations of TP53, CTNNB1, MEN1, and CDKN2A have been reported associated with ACC, and PRKAR1A, ZNRF3, RB1, APC, and RPL22 were also associated with ACC, based on recent researches (Zheng et al. 2016; Assié et al. 2014).