Compared with those in the normal control group, patients with ccRCC exhibited higher expression of PGK1, GPI, ALDOA, TPI1, GAPDH, ENO1, ALDOC, PDK1, LDHA, HK2, SHMT2, ENO2, HK3, SDS, PGLS, G6PD, and PRIA (Figure 3(c)). This evidence concerns the gene SHMT2 and nonpapillary renal cell carcinoma.