VDR and metabolic syndrome: Haplotype analysis of VDR gene polymorphisms (FokI-BsmI-ApaI-TaqI) has also been carried out in metabolic syndrome (MetS), where it was demonstrated that the CATT haplotype was associated with an increased risk of MetS (OR: 4.32, 95% CI: 1.32-14.10; p = 0.016), while the TGGT haplotype reduced the risk of MetS occurring in a Thai population (OR: 0.68, 95% CI: 0.48-0.98; p = 0.042) [53].