In a phase II randomized trial comparing polatuzumab vedotin (Pola) [43], an anti-CD79b antibody drug conjugate, in combination with bendamustine (B) and rituximab(R) versus BR for R/R DLBCL, the overall response rates were 45% and 17.5%, and the complete response rates were 40% and 15%, respectively. This evidence concerns the gene CD79B and diffuse large B-cell lymphoma.