VCAN and neoplasm: We found that higher expression levels of some genes were also associated with larger tumor size and advanced clinical stage such as collagen triple helix repeat containing 1 (CTHRC1), APC downregulated 1 like (APCDD1L), collagen type I alpha 1 chain (COL1A1), versican (VCAN), tenascin-C (TNC), and matrix metalloproteases 14 (MMP14).