APOM and colorectal carcinoma: To examine further the mechanism underlying the biological role of ApoM in CRC, ApoM overexpression (ApoM-OE) as well as negative control (ApoM-NC) Caco-2 cells were stably transduced with the RPS27A RNAi (RSP27A-KD) lentiviral vector and its negative control vector (RSP27A-NC), respectively.