Gunasekaran et al. found that RPS27A is downregulated in virus-induced hepatocellular carcinoma (HCC) patients and that its expression has a weak inverse relationship with overexpression of the multifunctional protein YB-1 in HCC tissues (Gunasekaran and Ganeshan, 2014[8]). The gene discussed is YBX1; the disease is hepatocellular carcinoma.