However, from GSE31821 dataset of the patients with AF and healthy subjects, twenty-one key pathways were discovered, including 1) Focal adhesion; 2) MAPK; 3) Amoebiasis; 4) Cancer; 5) PI3K-Akt; 6) Wnt signaling; 7) ECM-receptor interaction; 8) Platelet activation; 9) Toxoplasmosis; and 10) Proteoglycans in cancer (see Table 5(Tab. Here, AKT1 is linked to toxoplasmosis.