SLC5A2 and type 2 diabetes mellitus: The maximal SGLT2 glucose transport in patients with type 2 diabetes has been estimated at 500–600 g/d, representing a total of 2.75–3.3 moles of glucose (180 g/mol) [16] This reflects a maximal SGLT2 sodium reabsorption total of ~63–76 g/d (1 mole of sodium weighs 22.99 g).