Interestingly, expression of Slc11a1, which is also called natural resistance-associated macrophage protein 1 (Nramp1) and known to be a susceptibility gene for PNTM disease, was induced by infection in the lungs of wild-type mice, though expression of this gene was much lower in the infected lungs of Nrf2−/−mice than of wild-type mice. The gene discussed is SLC11A1; the disease is infection.