The CD8+ tumor uptake was significantly higher than that in CD8− tumor (24.08 ± 2.65% ID/g vs.1.59 ± 0.38% ID/g for 68Ga-NOTA-SNA006a, 15.34 ± 1.88% ID/g versus 1.40 ± 0.04% ID/g for 68Ga-NOTA-SNA006c, 15.06 ± 0.76% ID/g versus 1.14 ± 0.06% ID/g for 68Ga-NOTA-SNA006d at 1 h p.i., respectively). The gene discussed is CD8A; the disease is neoplasm.