Nonsense mutations that are predicted to be pathogenic and cancer-related in ClinVar are in RB1 in UM-MCC9 (rs794727481) and UM-MCC34 (rs121913304), in BAP1 in UM-MCC32 (chr3.52437267.G > A), and in the tumor-suppressor gene CHEK2 in MKL-1 (chr22.29091725.C > T). The gene discussed is BAP1; the disease is cancer.