In addition, both the analysis of publicly available microarray data and immunohistochemical analysis showed higher TRPM4 expression in the activated B cell-like DLBCL (ABC-DLBCL) subtype, and this increased expression was significantly correlated with worse overall survival in R-CHOP chemotherapy-treated DLBCL samples [33]. Here, TRPM4 is linked to diffuse large B-cell lymphoma.