In this regard, FAK deletion in breast CAFs was recently shown to enhance the cytokine signaling pathways and the expression of C–C Motif Chemokine Ligand 6 (Ccl6), C–C Motif Chemokine Ligand 11 (Ccl11), C–C Motif Chemokine Ligand 12 (Ccl12) and pentraxin-3, thus establishing a steady malignant cell glycolysis that facilitated the promotion of cancer cell growth [26]. This evidence concerns the gene PTK2 and cancer.