As a result, surface markers that have been used to identify other CSCs—such as CD24, CD44, CD90, CD133, and EpCAM—have been used to identify HCC CSCs, and intracellular markers, such as NANOG, OCT-3/4, and SOX2, have been used to identify HCC CSCs as well [23,38,98,99,101,102]. This evidence concerns the gene POU5F1 and hepatocellular carcinoma.