TP53 and oligodendroglioma: It has also been shown that IDH mutation status―along with other factors such as MGMT methylation, overexpression of p53 and 1p/19q codeletion―has a predictive value for PsP, with IDH-mutant tumors being more prone for PsP, which could also be reproduced in our cohort (14% PsP-rate in Astro-IDHwt vs. 48% in Astro-IDHmut and 45% in oligodendroglioma).