CD80 and neoplasm: Further, PANVAC is a therapeutic poxviral vaccine containing the genes for the tumor-associated antigens MUC-1 and carcinoembryonic antigen (CEA), as well as immunostimulatory genes CD80, intracellular adhesion molecule-1 (ICAM1), and leukocyte function-associated antigen-3 (LFA3) [23].