Three nonsynonymous ABCA1 polymorphisms have been extensively studied in terms of their associations with plasma lipid levels and CHD risk over the past two decades: rs2230806 (R219K) [32,33,34,35,36,37], rs2066714 (I883M) [33,35,38,39,40] and rs2230808 (R1587K) [33,38]. This evidence concerns the gene ABCA1 and coronary artery disorder.