Of these pathways, the regulation of proliferation, apoptosis, differentiation, survival, and pathways associated with cellular metabolism related to the phenotype induced by exposure to L-Tyr; while the p53, FoxO, apoptosis, Jak-STAT, and altered transcriptional regulation in cancer pathways related to the phenotype caused by exposure to 5-Brd-2′-dU. This evidence concerns the gene TP53 and cancer.