PFN1 and type 2 diabetes mellitus: Our analysis also showed that 21 downregulated DEGs (LONP1, RALY, PACS2, SH2D2A, DGKZ, MEPCE, KCTD13, ELF4, MFSD10, MAZ, SIGIRR, FCHO1, BCR, PPRC1, TPM2, IDUA, PFN1, LMF2, FLNA, APRT, and SLC10A3) were common between SCZ and T2DM (p < 0.0001 using a one-tailed chi-square test; representation factor = 2.5) (Figure 2).