The involvement of STAT1 is supported by data showing the activation of the IL23/JAK/STAT (Interleukin-23/ Janus Kinase/Signal Transducer and Activator of Transcription) pathway in T2DM PBMCs [64] and the activation of STAT1 in SCZ, which negatively correlated with cognitive performance [65]. This evidence concerns the gene STAT1 and type 2 diabetes mellitus.