SLC5A2 and hepatocellular carcinoma: Studies in vitro and in animal models documented such effect of dapagliflozin in case of CaKi-1 renal cell cancer line with high expression of SGLT-2 [128], canagliflozin in two cell lines of hepatocellular cancer [129], ipragliflozin, canagliflozin and dapagliflozin in breast cancer [130,131].